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M9470029.TXT
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1994-07-02
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Document 0029
DOCN M9470029
TI Neuropsychological impairment in human immunodeficiency virus-infection:
implications for employment. HNRC Group. HIV Neurobehavioral Research
Center [see comments]
DT 9409
AU Heaton RK; Velin RA; McCutchan JA; Gulevich SJ; Atkinson JH; Wallace MR;
Godfrey HP; Kirson DA; Grant I; University of California, San Diego,
School of Medicine.
SO Psychosom Med. 1994 Jan-Feb;56(1):8-17. Unique Identifier : AIDSLINE
MED/94255622
CM Comment in: Psychosom Med 1994 Jan-Feb;56(1):18-9
AB Individuals infected with the human immunodeficiency virus-Type 1
(HIV-1), are at increased risk for neurobehavioral impairment,
particularly in later stages of the disease. Even patients in the
medically asymptomatic or minimally symptomatic stages of infection may
show mild deficits on comprehensive neuropsychological (NP) test
batteries, although the clinical significance of such deficits remains
uncertain. The present study used vocational difficulties as markers of
clinical significance of NP impairment. In a sample of 289 HIV-infected,
nondemented men, those who evidenced NP impairment had a higher
unemployment rate (p < .001) than did their unimpaired counterparts. In
HIV-positive subjects who remained employed, NP impairment was strongly
associated with subjective decreases in job-related abilities. Neither
depression nor medical symptoms could explain the relationship between
the NP impairment and employment problems. These results are consistent
with previous studies investigating other neuropsychiatric disorders,
which suggest that even mild NP impairment can interfere with employment
status. From this standpoint, such impairment in HIV-infected persons
may be described as clinically significant.
DE Adult AIDS Dementia Complex/DIAGNOSIS/*REHABILITATION/TRANSMISSION
California Case Report Disability Evaluation Human HIV
Seropositivity/DIAGNOSIS/REHABILITATION/TRANSMISSION *HIV-1
Longitudinal Studies Male Military Personnel/STATISTICS & NUMER DATA
*Neuropsychological Tests *Rehabilitation, Vocational Sex Behavior
Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S.
Unemployment/STATISTICS & NUMER DATA JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).